The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2025
Filed:
Oct. 14, 2021
Shimadzu Corporation, Kyoto, JP;
National University Corporation Shimane University, Matsue, JP;
Takanari Hattori, Kyoto, JP;
Jun Watanabe, Kyoto, JP;
Tetsuo Iida, Kyoto, JP;
Misa Tanaka, Matsue, JP;
Hironori Kobayashi, Matsue, JP;
Shunji Tomatsu, Wilmington, DE (US);
SHIMADZU CORPORATION, Kyoto, JP;
NATIONAL UNIVERSITY CORPORATION SHIMANE UNIVERSITY, Matsue, JP;
Abstract
Provided is a method by which the disaccharides derived from glycosaminoglycans can be analyzed in a stable and highly reproducible manner. A method for analyzing a glycosaminoglycan according to the present invention includes: a first process for producing a plurality of kinds of disaccharides derived from a glycosaminoglycan in a biological sample by adding a plurality of kinds of glycosaminoglycan-specific enzymes to the biological sample; and a second process for separating and analyzing the plurality of kinds of disaccharides by a liquid chromatography-mass spectrometry method, where a column used for liquid chromatography in the liquid chromatography-mass spectrometry method is a column packed with a stationary-phase support to which an amide group as a functional group is bound, or a column packed with a stationary-phase support to which an adamantyl group as a functional group is bound.