The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2025

Filed:

Jun. 16, 2021
Applicant:

University of Central Florida Research Foundation, Inc., Orlando, FL (US);

Inventors:

Swaminathan Rajaraman, Winter Park, FL (US);

Avra Kundu, Orlando, FL (US);

Adam Rozman, Oviedo, FL (US);

Jorge Manrique Castro, Orlando, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); B29C 64/124 (2017.01); B33Y 10/00 (2015.01); B33Y 80/00 (2015.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/26 (2006.01); C12M 1/32 (2006.01); C12M 1/42 (2006.01); C12M 3/06 (2006.01); G01N 33/483 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
C12M 41/46 (2013.01); B29C 64/124 (2017.08); B33Y 10/00 (2014.12); B33Y 80/00 (2014.12); C12M 23/12 (2013.01); C12M 23/16 (2013.01); C12M 23/22 (2013.01); C12M 25/08 (2013.01); C12M 35/02 (2013.01); C12M 33/00 (2013.01); G01N 33/4836 (2013.01); G01N 2035/00158 (2013.01);
Abstract

A high-throughput, three-dimensional microelectrode array for in vitro electrophysiological applications includes a 3D printed well plate having a top face and bottom face, and a plurality of culture wells formed on the top face of the well plate. Each culture well includes a plurality of vertical microchannels on the top face and microtroughs formed on the bottom face and communicating with the microchannels. A conductive paste fills the microtroughs and the microchannels and forms self-isolated microelectrodes in each culture well and conductive traces that communicate with the self-isolated microelectrodes.


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