The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2025
Filed:
Sep. 19, 2023
Sanofi, Paris, FR;
Innate Pharma, Marseilles, FR;
Nicolas Gourdin, Marseilles, FR;
Laurent Gauthier, Marseilles, FR;
Alexandre Tang, Paris, FR;
Marielle Chiron, Paris, FR;
Angela Virone-Oddos, Paris, FR;
Alessandro Masiero, Paris, FR;
Jochen Beninga, Frankfurt am Main, DE;
Ingo Focken, Frankfurt am Main, DE;
Sambasiva Rao, Cambridge, MA (US);
Yanfeng Zhou, Cambridge, MA (US);
Leila Sevigny, Cambridge, MA (US);
Abstract
The present disclosure relates to multifunctional binding proteins comprising a first and a second antigen binding domains (ABDs) and all or part of an immunoglobulin Fc region or variant thereof, wherein the first ABD binds specifically to human BCMA and the second ABD binds specifically to human NKp46 and wherein all or part of the immunoglobulin Fc region or variant thereof bind to a human Fc-γ receptor. The disclosure also relates to methods for making said binding proteins, compositions thereof, and their uses, including the treatment or prevention of proliferative disorders, including multiple myeloma (MM).