The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2025
Filed:
Dec. 13, 2019
Remegen Co., Ltd., Yantai, CN;
Changjiang Huang, Yantai, CN;
Hui Ye, Yantai, CN;
Hu Chen, Yantai, CN;
Xiuzhi Zhan, Yantai, CN;
Nan Shen, Yantai, CN;
Wenting Luo, Yantai, CN;
Qiaohua Hou, Yantai, CN;
Jianmin Fang, Yantai, CN;
RemeGen Co., Ltd., Yantai, CN;
Abstract
The present invention provides a linker for preparing antibody-drug conjugates and antibody-drug conjugates prepared by the linker, as well as use of the antibody-drug conjugates in a medicament for treating tumor. The linker is capable of coupling simultaneously with the thiol group or amino group on the antibody or functional fragment of the antibody, especially it is capable of coupling with 2, 3 or 4 thiol groups on the antibody or functional fragment of the antibody. A coupled product is uniform and structurally stable.