The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2025
Filed:
Dec. 18, 2023
Sanofi, Paris, FR;
Gerald Beste, Ghent, BE;
Yanik Bruynooghe, Ghent, BE;
Klervi Desrumeaux, Paris, FR;
Jennifer Kuehn, Frankfurt am Main, DE;
Charlotte Lahoute, Paris, FR;
Rami Lissilaa, Paris, FR;
Alessandro Masiero, Paris, FR;
Sevim Oezguer Bruederle, Frankfurt am Main, DE;
Benjamin Suratt, Cambridge, MA (US);
Emmanuelle Vigne, Paris, FR;
Jessica Voss, Cambridge, MA (US);
SANOFI, Paris, FR;
Abstract
Provided herein are multispecific binding proteins comprising (a) a first antigen binding domain (ABD) comprising an immunoglobulin single variable domain (ISVD) (e.g., VHH) with binding specificity to CD28; and (b) a second ABD comprising an immunoglobulin heavy chain variable domain (VH) and an immunoglobulin light chain variable domain (VL) with binding specificity to OX40. Also provided are methods of treating autoimmune diseases with said multispecific binding proteins.