The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2025

Filed:

May. 12, 2023
Applicant:

Akeso Biopharma, Inc., Guangdong, CN;

Inventors:

Baiyong Li, Zhongshan, CN;

Yu Xia, Zhongshan, CN;

Zhongmin Maxwell Wang, Zhongshan, CN;

Peng Zhang, Zhongshan, CN;

Assignee:

AKESO BIOPHARMA, INC., Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/22 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 47/6849 (2017.08); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); A61K 2039/505 (2013.01);
Abstract

The present application relates to the fields of tumor treatment and molecular immunology, and specifically, to an anti-VEGFA/PD-1 bifunctional antibody, a pharmaceutical composition thereof and use thereof. Specifically, the anti-VEGFA/PD-1 bifunctional antibody comprises an antibody or antigen binding fragment thereof targeting VEGFA and an antibody or antigen binding fragment thereof targeting PD-1. The bifunctional antibody can specifically bind to VEGFA and PD-1, specifically relieve immunosuppression of VEGFA and PD-1 in an organism, and inhibit tumor-induced angiogenesis.


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