The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2025
Filed:
Apr. 30, 2021
Applicant:
Acceleron Pharma Inc., Cambridge, MA (US);
Inventors:
Ravindra Kumar, Cambridge, MA (US);
Dianne S. Sako, Cambridge, MA (US);
Assignee:
Acceleron Pharma Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/71 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/71 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01);
Abstract
In certain aspects, the present disclosure relates to TβRII fusion polypeptides comprising a heterologous portion and a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders.