The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2025

Filed:

May. 25, 2021
Applicant:

Sanofi, Paris, FR;

Inventors:

Stefan Guessregen, Frankfurt am Main, DE;

Martin Will, Frankfurt am Main, DE;

Thomas Boehme, Frankfurt am Main, DE;

Marcus Hermann Korn, Frankfurt am Main, DE;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/62 (2006.01); A61K 31/18 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); A61K 31/18 (2013.01); A61K 47/64 (2017.08);
Abstract

The present invention relates to a conjugate comprising a sulfonamide of formula (I) and an active pharmaceutical ingredient such as an insulin analog comprising at least one mutation relative to the parent insulin, wherein the insulin analog comprises a mutation at position B16 which is substituted with a hydrophobic amino acid and/or a mutation at position B25 which is substituted with a hydrophobic amino acid. The present invention further relates to a sulfonamide of formula (A). Moreover, the present invention relates to an insulin analog comprising at least one mutation relative to the parent insulin.


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