The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2025

Filed:

Dec. 01, 2020
Applicant:

Storm Therapeutics Limited, Cambridge, GB;

Inventors:

Wesley Peter Blackaby, Cambridge, GB;

Elizabeth Jane Thomas, Cambridge, GB;

David James Hardick, Cambridge, GB;

Jon Shepherd, Oxfordshire, GB;

Frederick Arthur Brookfield, Oxfordshire, GB;

Christian Bubert, Oxfordshire, GB;

Mark Peter Ridgill, Oxfordshire, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 403/14 (2013.01); C07D 417/14 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to compounds of formula (I) that function as inhibitors of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity:X—Y—Z   (I)wherein X, Y and Z are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, and autoimmune diseases, as well as other diseases or conditions in which METTL3 activity is implicated.


Find Patent Forward Citations

Blackaby, Wesley. (2025). Polyheterocyclic compounds as mettl3 inhibitors (U.S. Patent No. 12195458). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12195458

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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