The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2025
Filed:
Aug. 06, 2019
Applicant:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Inventors:
Samuel D. Banister, Castle Hill, AU;
Edgar Engleman, Redwood City, CA (US);
Khoa D. Nguyen, Redwood City, CA (US);
Mark Smith, Redwood City, CA (US);
Assignee:
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 235/08 (2006.01); C07D 235/18 (2006.01); C07D 263/57 (2006.01); C07D 277/66 (2006.01); C07D 401/04 (2006.01); C07D 417/04 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07F 9/6506 (2006.01);
U.S. Cl.
CPC ...
C07D 235/08 (2013.01); C07D 235/18 (2013.01); C07D 263/57 (2013.01); C07D 277/66 (2013.01); C07D 401/04 (2013.01); C07D 417/04 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07F 9/65068 (2013.01); C07B 2200/05 (2013.01);
Abstract
A genus of compounds encompassed by formula (III) and their use is disclosed: The compounds activate Ppargc1a and, as a consequence, are useful for treating a variety of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, Huntington's disease, frontotemporal degeneration, dementia with Lewy bodies, motor neuron diseases, and a demyelinating disease.