The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2025

Filed:

Aug. 26, 2022
Applicant:

Curevac Manufacturing Gmbh, Tübingen, DE;

Inventors:

Thomas Ketterer, Gomaringen, DE;

Thorsten Mutzke, Reutlingen, DE;

Michael Wiggenhorn, Munich, DE;

Frank Schaubhut, Germering, DE;

Florian Von Der Mülbe, Stuttgart, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 9/19 (2006.01); A61K 31/7105 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); C12Q 1/6806 (2018.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
A61K 9/19 (2013.01); A61K 31/7105 (2013.01); A61K 47/549 (2017.08); A61K 47/64 (2017.08); C12Q 1/6806 (2013.01); C12N 15/1003 (2013.01);
Abstract

The present invention is directed to the field of RNA formulation, in particular to lyophilization of RNA. The invention provides a method for lyophilization of RNA. The present invention further concerns a lyophilized composition obtainable by the inventive method, a pharmaceutical composition, a vaccine and a kit or kit of parts. Moreover, the present invention provides a novel use of a lyoprotectant for lyophilizing RNA, the use of the inventive method in the manufacture of a medicament as well as the first and second medical use of the composition obtainable by the inventive method, the pharmaceutical composition, the vaccine or the kit or kit of parts according to the invention.


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