The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2025

Filed:

Jan. 24, 2023
Applicants:

Emory University, Atlanta, GA (US);

Indian Institute of Science;

Inventors:

Rama Rao Amara, Decatur, GA (US);

Andrew Jones, Atlanta, GA (US);

Raghavan Varadarajan, Bengaluru, IN;

Assignees:

Emory University, Atlanta, GA (US);

Indian Institute of Science, Bangalore, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); A61K 39/21 (2006.01); C07K 14/155 (2006.01); C07K 14/16 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); C07K 14/162 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); C12N 2710/24143 (2013.01); C12N 2740/16034 (2013.01);
Abstract

This disclosure relates to methods of promoting immune responses against HIV and compositions related thereto. In certain embodiments, this disclosure relates to methods of vaccinating for HIV comprising administering to the subject a priming composition followed by a boosting composition. In certain embodiments, the priming composition comprises a recombinant virus such as recombinant MVA that encodes an Env protein of HIV or segment thereof. In certain embodiments, the boosting composition comprises a trimeric cyclically permuted gp120 chimeric protein reported herein or DNA encoding the same.


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