The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2025
Filed:
Apr. 05, 2024
Applicant:
Axsome Malta Ltd., Qormi, MT;
Inventor:
Katayoun Zomorodi, San Jose, CA (US);
Assignee:
AXSOME MALTA LTD., Qormi, MT;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/325 (2006.01); A61B 5/00 (2006.01); A61B 5/20 (2006.01); A61K 9/00 (2006.01); A61K 31/27 (2006.01); A61P 25/26 (2006.01);
U.S. Cl.
CPC ...
A61K 31/325 (2013.01); A61B 5/201 (2013.01); A61B 5/4839 (2013.01); A61K 9/0053 (2013.01); A61K 31/27 (2013.01); A61P 25/26 (2018.01);
Abstract
The invention relates to methods for decreasing adverse effects associated with solriamfetol ([R]-2-amino-3-phenylpropylcarbamate) therapy in subjects with impaired renal function. In particular, the invention provides an optimized dose escalation scheme for subjects with moderate renal impairment which results in the subjects having increased tolerance to adverse effects associated with the administration of solriamfetol. The invention also provides adjusted dosing for safe therapeutic use of solriamfetol in subjects having severe renal impairment.