The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Sep. 13, 2019
Applicant:

Immatics Biotechnologies Gmbh, Tuebingen, DE;

Inventors:

Andreas Moritz, Tuebingen, DE;

Dominik Maurer, Moessingen, DE;

Sebastian Bunk, Tuebingen, DE;

Claudia Wagner, Tuebingen, DE;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/74 (2006.01); G01N 33/569 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56977 (2013.01); A61K 38/1774 (2013.01); A61K 39/00 (2013.01); A61K 39/39541 (2013.01); C07K 14/70539 (2013.01); A61K 2039/505 (2013.01); A61K 2039/57 (2013.01); G01N 2333/7051 (2013.01); G01N 2333/70539 (2013.01);
Abstract

The present invention relates to a method for high throughput screening for a TCR-binding peptide ligand/MHC molecule complex, comprising a stabilized peptide-MHC molecule and respective uses of said method. The present invention further relates to polypeptides comprising or consisting of stabilized MHC molecules or peptide binding fragments thereof, pharmaceutical compositions comprising said polypeptides, vaccines comprising said pharmaceutical composition and uses of said vaccine for the manufacturing of a medicament and/or in the prevention of cancer The present invention further relates to nucleic acids encoding said polypeptides and vectors comprising said nucleic acids.


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