The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Feb. 24, 2023
Applicant:

National Taiwan University, Taipei, TW;

Inventors:

Chi-Kuang Sun, Taipei, TW;

Xu-hao Ye, Taipei, TW;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/31 (2006.01); G01N 33/49 (2006.01); G02B 21/00 (2006.01); G02B 27/10 (2006.01); G02B 27/14 (2006.01);
U.S. Cl.
CPC ...
G01N 21/3103 (2013.01); G01N 33/49 (2013.01); G02B 21/0032 (2013.01); G02B 21/0064 (2013.01); G02B 27/1013 (2013.01); G02B 27/141 (2013.01); G02B 27/145 (2013.01);
Abstract

A microscope is provided to measure HbA1c fraction. The microscope measures the HbA1c fraction of a single red blood cell (RBC) in a trace blood sample. The HbA1c fraction can be measured through a non-invasive way while the RBC flows in a human epidermal microvessel, too. The microscope comprises a laser device, an upright microscope, a light splitter, a light detector, and a mainframe. Unlike traditional methods, the HbA1c fraction can be measured in vitro or in vivo at the level of a single RBC. Accurate measurement is achieved. Misdiagnosis rate is reduced. The microscope provides HbA1c fractions from hundreds of RBCs, instead of averaging HbA1c fractions obtained from a large number of blood samples. Hence, the present invention is a method of detecting a HbA1c fraction of a single RBC, and is a microscope supporting blood-drawing measurement and non-invasive measurement simultaneously.


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