The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2025
Filed:
Mar. 29, 2019
Applicant:
The University of Liverpool, Liverpool Merseyside, GB;
Inventor:
Anthony Hollander, Liverpool, GB;
Assignee:
THE UNIVERSITY OF LIVERPOOL, Liverpool, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/64 (2006.01); A61K 47/50 (2017.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6491 (2013.01); A61K 47/50 (2017.08); C07K 14/47 (2013.01); C12Y 304/24024 (2013.01);
Abstract
Provided are peptides, and conjugates comprising targeting peptides and payloads. The peptides comprise a plurality of modules corresponding to at least one of module 1, module 2, or module 3 of the collagen binding domain of a gelatinase, or a gelatin-binding fragment or variant thereof. The gelatinase may be MMP-2. The conjugates may be therapeutic or non-therapeutic. Medical uses of the peptides or therapeutic conjugates, and pharmaceutical compositions comprising these, are also provided, as are nucleic acids encoding the peptides.