The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Aug. 27, 2019
Applicants:

Vanderbilt University, Nashville, TN (US);

Baylor College of Medicine, Houston, TX (US);

Inventors:

James E. Crowe, Jr., Nashville, TN (US);

Mary Estes, Houston, TX (US);

Assignees:

VANDERBILT UNIVERSITY, Nashville, TN (US);

BAYLOR COLLEGE OF MEDICINE, Houston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C07K 16/10 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); C07K 16/10 (2013.01); G01N 33/56983 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/76 (2013.01); G01N 2333/08 (2013.01);
Abstract

The present disclosure is directed to antibodies binding to and neutralizing norovirus and methods for use thereof. Thus, in accordance with the present disclosure, there is provided a method of detecting a norovirus infection in a subject comprising (a) contacting a sample from the subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences; and (b) detecting norovirus in the sample by binding of the antibody or antibody fragment to a norovirus antigen in the sample.


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