The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Nov. 26, 2019
Applicants:

Emory University, Atlanta, GA (US);

Georgia Tech Research Corporation, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Inventors:

Reginald Tran, Atlanta, GA (US);

Wilbur Lam, Atlanta, GA (US);

David Myers, Atlanta, GA (US);

Christopher Doering, Atlanta, GA (US);

Harold Spencer, Marietta, GA (US);

Assignees:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Georgia Tech Research Corporation, Atlanta, GA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 15/87 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 15/87 (2013.01);
Abstract

The systems and methods are directed to leveraging the channel geometry and configuration to overcome diffusion limitations of current transduction systems. The methods may include a method of transducing target cells using a device. The device may include at least one continuous channel. The method may include delivering target cells and viral vectors into a transduction region of the channel. After transducing for some incubation time, a flushing solution may be delivered. The method may include collecting transduced cells after the transducing incubation time and the delivering of the flushing solution.


Find Patent Forward Citations

Loading…