The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Apr. 18, 2023
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Binata Joddar, El Paso, TX (US);

David A. Roberson, El Paso, TX (US);

Naveen Nagiah, El Paso, TX (US);

Zayra N. Dorado, El Paso, TX (US);

Ivana Hernandez, El Paso, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 15/32 (2006.01); B29C 71/04 (2006.01); C07D 307/52 (2006.01); C08J 3/24 (2006.01); C08J 3/28 (2006.01); C08L 67/04 (2006.01); C08L 89/00 (2006.01); C08L 89/06 (2006.01); C08L 101/14 (2006.01); C12N 5/00 (2006.01); C12N 5/077 (2010.01); D01D 5/00 (2006.01); D01D 5/34 (2006.01); D01F 8/14 (2006.01); D06M 10/00 (2006.01);
U.S. Cl.
CPC ...
C08L 67/04 (2013.01); C08L 89/00 (2013.01); C12N 5/0062 (2013.01); C12N 5/0657 (2013.01); D01D 5/0038 (2013.01); D06M 10/001 (2013.01); C08L 2203/12 (2013.01); C12N 2500/38 (2013.01); C12N 2513/00 (2013.01); C12N 2533/30 (2013.01); C12N 2533/54 (2013.01); C12N 2537/10 (2013.01);
Abstract

Cardiac tissue-on-a-chip platforms aimed at mimicking human cardiac tissue structures, are valuable tools to model, and serve as preclinical platforms for drug testing or therapies for cardiac repair. We have developed three types of electrospun scaffolds including furfuryl gelatin (f-gelatin) alone, with polycaprolactone (PCL) in the ratio of f-gelatin and PCL (1:1), and coaxial scaffolds with PCL (core) and f-gelatin (sheath). Scaffolds were developed through single nozzle electrospinning and coaxial electrospinning, respectively, to serve as scaffolds for cardiac tissue-on-a-chip platforms.


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