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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12187817 B1

PDFFull Text
Date of Patent:
Jan. 07, 2025

Filed:

Aug. 02, 2023

Preparation of ceramide conjugates and derivatives of sphingolipid analogues

Applicant:

Kode Biotech Limited, Auckland, NZ;

Inventors:

Nicolai Vladimirovich Bovin, Moscow, RU;

Stephen Micheal Henry, Auckland, NZ;

Alexander Borisovich Tuzikov, Moscow, RU;

Assignee:

KODE BIOTECH LIMITED, Auckland, NZ;

Attorney:

NIXON & VANDERHYE

Primary Examiner:

Christina Bradley

Int. Cl.
CPC ...
C07K 9/00 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); C07K 1/107 (2006.01); C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
C07K 9/001 (2013.01); A61K 47/545 (2017.08); A61K 47/549 (2017.08); A61K 47/64 (2017.08); C07K 1/1077 (2013.01); C07K 19/00 (2013.01);
Abstract

The preparation of water dispersible ceramide conjugates and derivatives of sphingolipid analogues is described. The conjugates and analogues are prepared by reacting a succinimidyl carbonate of a β-Ala derivative with the primary amine of a functionalised spacer. Despite their dispersibility in water, the ceramide conjugates and derivatives of sphingolipid analogues spontaneously incorporate in to the plasma membranes of cells.

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Bovin, Nicolai. (2025). Preparation of ceramide conjugates and derivatives of sphingolipid analogues (U.S. Patent No. 12187817). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12187817

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