The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2025
Filed:
Jul. 26, 2019
Cisbio Bioassays, Codolet, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Institut National DE LA Sante ET DE LA Recherche Medicale (Inserm), Paris, FR;
Thomas Fabien Michel Roux, Nîmes, FR;
Elodie Julie Dupuis, Caissargues, FR;
Eric Jacques Christian Trinquet, Pont-Saint-Esprit, FR;
Mélanie Da Silva, Saint-Macoux, FR;
Camille S. Mailhac, Marseilles, FR;
Patrick J M Chames, Marseilles, FR;
Daniel Baty, Marseilles, FR;
Julien Jean-Marius Soule, Montpellier, FR;
Philippe Rondard, Saint-Gély-du-Fesc, FR;
Jean-Philippe R. Pin, Montpellier, FR;
CISCIO BIOASSAYS, Codolet, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), Paris, FR;
Abstract
The present invention relates to a single-domain antibody (sdAb) which binds to the G protein alpha, comprising an amino acid sequence consisting of 3 CDR regions (CDR1 to CDR3) and 4 hinge regions (FR1 to FR4) according to the following formula (I): FR1-CDR1-FR2-CDR2-FR3-CDR3-FR4 (I) and advantageously having a dissociation constant (Kd), measured in FRET, of less than 100 nM.