The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Mar. 21, 2018
Applicant:

Fundação Butantan, Butantã, BR;

Inventors:

Ana Marisa Chudzinski-Tavassi, Butantã, BR;

Mauricio Barbugiani Goldfeder, Vila Mariana, BR;

Asif Iqbal, Jardim Rizzo, BR;

Assignee:

Fundação Butantan, Butantã, BR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/81 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/811 (2013.01); A61K 38/00 (2013.01);
Abstract

A class of proteins that inhibit thrombin, particularly direct inhibitor of thrombin modified from sculptin, identified in the transcriptomics analysis of the salivary glands of ticks, as well as fragments and recombinant protein thereof, which can be used as anticoagulant agents and for the prophylaxis and/or treatment of thromboembolic diseases. These proteins fall within the fields of biochemistry, molecular biology, genetics, pharmacy and medicinal chemistry, being related to biochemical and metabolic processes.


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