The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

May. 26, 2021
Applicant:

Microsoft Technology Licensing, Llc, Redmond, WA (US);

Inventors:

Bichlien Hoang Nguyen, Seattle, WA (US);

Karin Strauss, Seattle, WA (US);

Jake Allen Smith, Seattle, WA (US);

Richard Prescott Rouse, Redmond, WA (US);

Douglas Mitchell Carmean, Seattle, WA (US);

Matthew David Turner, Carnation, WA (US);

Gagan Gupta, Redmond, WA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); B01J 19/00 (2006.01); B01J 19/12 (2006.01);
U.S. Cl.
CPC ...
C07H 21/04 (2013.01); B01J 19/0046 (2013.01); B01J 19/121 (2013.01); B01J 19/123 (2013.01); B01J 2219/00527 (2013.01); B01J 2219/00711 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/0879 (2013.01); B01J 2219/1203 (2013.01);
Abstract

Photon generating substrates for light-directed oligonucleotide synthesis are disclosed. Light is generated within a solid-state stack that supports growing oligonucleotides. The light may be generated by microLEDs, a pass-through liquid crystal panel, or an LCoS system. Light passes through a transmissive layer on which growing oligonucleotides are attached. Patterning of the light is controlled by selective activation of the microLEDs or by selective control of the transparency of a liquid crystal layer. Photolabile blocking groups are selectively removed by exposure to patterned light emitted from the photon generating substrate.


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