The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Mar. 13, 2020
Applicant:

Canget Biotekpharma Llc, Buffalo, NY (US);

Inventors:

Xiang Ling, Amherst, NY (US);

Qingyong Li, Hangzhou, CN;

Fengzhi Li, Buffalo, NY (US);

Assignee:

Canget BioTekpharma LLC, Buffalo, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 491/22 (2006.01); A61K 9/20 (2006.01); A61K 45/06 (2006.01); A61K 47/40 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C07D 491/22 (2013.01); A61K 47/40 (2013.01); A61K 9/0053 (2013.01); A61K 9/20 (2013.01); A61K 45/06 (2013.01);
Abstract

Described herein, are the chemical synthesis, matter of compositions, formulation, function, methods and uses of the FL118 platform Positions 7 and/or 9-derived analogues for treating cancer or other human diseases. Compounds derived from chemical modifications of the FL118 platform are employed alone or in combination with other anti-cancer agents to preclude, eliminate or reverse cancer phenotypes. This invention intends to realize unique personalized cancer treatment (personalized precision medicine) through application of a series of structural relevant individual FL118 platform-derived analogues, which target multiple cellular human disease-relevant proteins and their signaling pathways.


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