The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Aug. 24, 2023
Applicant:

Incyte Corporation, Wilmington, DE (US);

Inventors:

Yanran Ai, West Chester, PA (US);

Yu Bai, Claymont, DE (US);

Joseph Barbosa, Lambertville, NJ (US);

Hao Feng, Glen Mills, PA (US);

Leah C. Konkol, Newark, DE (US);

Xun Liu, Glenn Mills, PA (US);

Jun Pan, Media, PA (US);

Haisheng Wang, Hockessin, DE (US);

Liangxing Wu, Wilmington, DE (US);

Wenqing Yao, Chadds Ford, PA (US);

Eddy W. Yue, Landenberg, PA (US);

Assignee:

Incyte Corporation, Wilmington, DE (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); C07D 471/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 519/00 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present application provides tricyclic urea compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.


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