The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2025
Filed:
Mar. 13, 2020
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Xu Wu, Lexington, MA (US);
Pranab Maiti, Hyderabad, IN;
Chandrasekhar Abbineni, Hyderabad, IN;
Krishna Chaitanya Talluri, Hyderabad, IN;
Sunil Kumar Panigrahi, Boudh, IN;
Gopala Krishna Jarugumilli, Malden, MA (US);
Yang Sun, Quincy, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/165 (2006.01); A61K 31/18 (2006.01); A61K 31/195 (2006.01); A61K 31/196 (2006.01); A61K 31/24 (2006.01); A61K 31/397 (2006.01); A61K 31/401 (2006.01); A61K 31/405 (2006.01); A61K 31/41 (2006.01); A61K 31/416 (2006.01); A61K 31/4184 (2006.01); A61K 31/4196 (2006.01); A61K 31/428 (2006.01); A61K 31/44 (2006.01); A61K 31/4439 (2006.01); A61K 31/4704 (2006.01); A61K 31/496 (2006.01); A61K 31/4965 (2006.01); C07C 211/26 (2006.01); C07C 211/55 (2006.01); C07C 211/56 (2006.01); C07C 211/60 (2006.01); C07C 225/22 (2006.01); C07C 229/44 (2006.01); C07C 229/48 (2006.01); C07C 229/58 (2006.01); C07C 237/40 (2006.01); C07C 255/58 (2006.01); C07C 311/44 (2006.01); C07C 317/28 (2006.01); C07C 323/63 (2006.01); C07D 205/04 (2006.01); C07D 207/16 (2006.01); C07D 207/34 (2006.01); C07D 209/08 (2006.01); C07D 211/62 (2006.01); C07D 213/74 (2006.01); C07D 213/79 (2006.01); C07D 213/80 (2006.01); C07D 215/227 (2006.01); C07D 231/14 (2006.01); C07D 231/56 (2006.01); C07D 233/61 (2006.01); C07D 233/64 (2006.01); C07D 235/06 (2006.01); C07D 235/08 (2006.01); C07D 235/18 (2006.01); C07D 239/42 (2006.01); C07D 239/48 (2006.01); C07D 239/88 (2006.01); C07D 241/20 (2006.01); C07D 241/28 (2006.01); C07D 249/08 (2006.01); C07D 249/10 (2006.01); C07D 257/04 (2006.01); C07D 275/06 (2006.01); C07D 277/28 (2006.01); C07D 295/135 (2006.01); C07D 295/155 (2006.01); C07D 317/32 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07C 211/55 (2013.01); C07C 211/56 (2013.01); C07C 229/44 (2013.01); C07C 229/48 (2013.01); C07C 229/58 (2013.01); C07C 237/40 (2013.01); C07C 255/58 (2013.01); C07C 311/44 (2013.01); C07D 205/04 (2013.01); C07D 207/16 (2013.01); C07D 209/08 (2013.01); C07D 211/62 (2013.01); C07D 213/74 (2013.01); C07D 213/80 (2013.01); C07D 215/227 (2013.01); C07D 231/56 (2013.01); C07D 233/61 (2013.01); C07D 235/18 (2013.01); C07D 239/42 (2013.01); C07D 241/28 (2013.01); C07D 249/08 (2013.01); C07D 275/06 (2013.01); C07D 295/135 (2013.01); C07D 317/32 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01);
Abstract
The present disclosure compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the TEAD transcription factor, and are useful in the treatment of diseases related to the activity of TEAD transcription factor including, e.g., cancer and other diseases.