The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2025
Filed:
Jan. 13, 2020
Applicant:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Inventors:
Daniel O'Malley, New Hope, PA (US);
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Derek J. Norris, Pennington, NJ (US);
Hua Gong, King of Prussia, PA (US);
Yong Zhang, West Windsor, NJ (US);
Patrice Gill, Levittown, PA (US);
Christine M. Tarby, Lawrenceville, NJ (US);
Matthias Broekema, New Hope, PA (US);
Scott Hunter Watterson, Pennington, NJ (US);
Assignee:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61K 45/06 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01);
Abstract
The present invention provides compounds of Formula (I): Formula (I) wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).