The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Jul. 31, 2019
Applicant:

Guangzhou Magpie Pharmaceuticals Co., Ltd., Guangdong, CN;

Inventors:

Wei Liu, Guangzhou, CN;

Yewei Sun, Guangzhou, CN;

Yuqiang Wang, Guangzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/12 (2006.01); A61K 31/4965 (2006.01);
U.S. Cl.
CPC ...
C07D 241/12 (2013.01); C07B 2200/13 (2013.01);
Abstract

A crystal form of tetramethylpyrazine nitrone (TBN), and a preparation method and use thereof is provided. A crystal form A of TBN has characteristic diffraction peaks in the XRPD pattern at 2θ°: 10.60±0.2, 11.03±0.2, 15.31±0.2, 15.55±0.2, 17.14±0.2, 17.93±0.2, and 23.81±0.2. The crystal form A has low risk of polymorphism transformation and good stability, which contribute to the stability of the preparations during the production and storage processes, and effectively guarantee the consistency of the content of the crystal form in the preparations. Therefore, the preparations are safe, effective, and controllable in quality. Also, the crystal form A has high biological activity, good druggability, and high bioavailability, fast onset of action.


Find Patent Forward Citations

Loading…