The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Dec. 09, 2016
Applicant:

University of Cincinnati, Cincinnati, OH (US);

Inventors:

Aaron Seitz, Cincinnati, OH (US);

Michael J. Edwards, Cincinnati, OH (US);

Erich Gulbins, Cincinnati, OH (US);

Assignee:

University of Cincinnati, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 29/16 (2006.01); A61M 16/04 (2006.01); A61M 25/00 (2006.01);
U.S. Cl.
CPC ...
A61L 29/16 (2013.01); A61M 16/04 (2013.01); A61L 2300/22 (2013.01); A61L 2300/404 (2013.01); A61M 25/0009 (2013.01); A61M 25/0017 (2013.01); A61M 25/0045 (2013.01); A61M 2205/0205 (2013.01); A61M 2205/0238 (2013.01); A61M 2207/00 (2013.01);
Abstract

Methods for applying a sphingolipid aggregate coating to a surface of a substrate for inhibition and prevention of biofilm growth, methods for inhibiting and preventing biofilms, biofilm-inhibiting coatings and coated devices are provided. Coating processes include suspending an amount of sphingolipid in a medium-to-fast-evaporating organic solvent; b) applying energy to the suspension sufficient to create a colloidal dispersion of sphingolipid in the solvent; c) heating the dispersion sufficient to create a solution; and d) coating the surface of the substrate with at least one application of solution, each application followed directly by a complete solvent evaporation period. The resulting coatings exhibit aggregate architectures particularly effective for inhibition and prevention of biofilms.


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