The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2025
Filed:
Feb. 14, 2023
Eagle Pharmaceuticals, Inc., Woodcliff Lake, NJ (US);
Feng-Jing Chen, Irvine, CA (US);
Steven L. Krill, Midland Park, NJ (US);
Rama Abu Shmeis, Branchburg, NJ (US);
Adrian Hepner, Ramsey, NJ (US);
Charles Wescott, Woodcliff Lake, NJ (US);
Tara Jaskowski, Woodcliff Lake, NJ (US);
Michael Joyce, Woodcliff Lake, NJ (US);
Eagle Pharmaceuticals, Inc., Woodcliff Lake, NJ (US);
Abstract
The present disclosure provides methods of treating breast cancer including administering aqueous suspensions com-prising solubilized fulvestrant, non-solubilized fulvestrant particles having one or more of an LD Dv(1 0) between about 1.5 and about 2.1 microns, an LD Dv(50) between about 5.5 and about 9.0 microns, and an LD Dv(90) between about 15 and about 35 microns, with the aqueous suspensions further including a surfactant, a polyvinylpyrrolidone, and a sugar alcohol, and a water-soluble excipient. The water-soluble excipient can be an aryl-Ci-6alk-OH, a Ci-6alkyl-OH, a buffering salt, a polysorbate, a polyalkylene glycol, a Ci-i2alkylene glycol, a phosphatidylcholine, or a combination thereof.