The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Apr. 19, 2023
Applicant:

The University of Chicago, Chicago, IL (US);

Inventors:

Jeffrey A. Hubbell, Chicago, IL (US);

Ruyi Wang, Chicago, IL (US);

D. Scott Wilson, Chicago, IL (US);

Cathryn R. Nagler, Chicago, IL (US);

Catherine Plunkett, Chicago, IL (US);

Assignee:

The University of Chicago, Chicago, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/58 (2017.01); A61K 45/06 (2006.01); A61K 47/69 (2017.01); C08F 293/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/58 (2017.08); C08F 293/005 (2013.01); A61K 45/06 (2013.01); A61K 47/6907 (2017.08); A61K 47/6929 (2017.08); C08F 2438/03 (2013.01);
Abstract

Provided herein are polymer materials that find use in, for example, delivery of short-chain fatty acids. In particular, polymers are provided that form stable nanoscale structures and release their payload, for example, by cleavage of a covalent bond (e.g., via hydrolysis or enzymatic cleavage). The polymers are useful, for example, for delivery of payloads (e.g., SCFAs) to the intestine for applications in health and treatment of disease, and have broad applicability in diseases linked to changes in the human microbiota including inflammatory, autoimmune, allergic, metabolic, and central nervous system diseases, among others.


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