The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Dec. 04, 2020
Applicant:

Bioverativ Therapeutics Inc., Waltham, MA (US);

Inventors:

Jennifer A. Dumont, Groton, MA (US);

Susan Low, Pepperill, MA (US);

Alan J. Bitonti, Acton, MA (US);

Glenn Pierce, Rancho Santa Fe, CA (US);

Alvin Luk, Boston, MA (US);

Haiyan Jiang, Belmont, MA (US);

Byron McKinney, San Diego, CA (US);

Matt Ottmer, Newton, MA (US);

Jurg Sommer, Wayland, MA (US);

Karen Nugent, Owlswick, GB;

Lian Li, Lexington, MA (US);

Robert T. Peters, Needham, MA (US);

Assignee:

BIOVERATIV THERAPEUTICS INC., Waltham, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/37 (2006.01); A61K 47/60 (2017.01); A61K 47/68 (2017.01); C07K 14/755 (2006.01); G01N 33/86 (2006.01);
U.S. Cl.
CPC ...
A61K 38/37 (2013.01); A61K 47/60 (2017.08); A61K 47/68 (2017.08); C07K 14/755 (2013.01); G01N 33/86 (2013.01); C07K 2319/00 (2013.01); C07K 2319/31 (2013.01);
Abstract

The present invention provides methods of administering Factor VIII (processed FVIII, single chain FVIII, or a combination thereof); methods of administering chimeric and hybrid polypeptides comprising Factor VIII; chimeric and hybrid polypeptides comprising Factor VIII; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.


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