logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12186369 B1

PDFFull Text
Date of Patent:
Jan. 07, 2025

Filed:

Sep. 20, 2018

Gene therapy strategy to restore electrical and cardiac function, and cardiac structure, in arrhythmogenic right ventricular cardiomyopathy

Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Farah Sheikh, La Jolla, CA (US);

Jing Zhang, La Jolla, CA (US);

Assignee:

The Regents of the University of California, Oakland, CA (US);

Attorney:

Perkins Coie LLP

Primary Examiner:

M Franco G Salvoza

Int. Cl.
CPC ...
C12N 15/00 (2006.01); A61K 35/761 (2015.01); A61K 38/17 (2006.01); A61P 9/06 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/177 (2013.01); A61K 35/761 (2013.01); A61P 9/06 (2018.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2710/10343 (2013.01); C12N 2750/14143 (2013.01);
Abstract

Disclosed herein are methods of treating arrhythmogenic right ventricular cardiomyopathy in a subject, comprising administering a gene therapy construct comprising a connexin 43 sequence, wherein as a result of the administration, connexin 43 levels in at least a portion of the heart are increased. Further disclosed are other cardiovascular diseases can be treated with the method.

Find Patent Forward Citations

Quick Actions:

Sheikh, Farah. (2025). Gene therapy strategy to restore electrical and cardiac function, and cardiac structure, in arrhythmogenic right ventricular cardiomyopathy (U.S. Patent No. 12186369). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12186369

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…