The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Apr. 13, 2022
Applicants:

Tigenix, S.a.u., Madrid, ES;

Consejo Superior DE Investigaciones Cientificas, Madrid, ES;

Inventors:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/35 (2015.01); A61K 35/12 (2015.01); A61K 39/00 (2006.01); C12N 5/0775 (2010.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
A61K 35/35 (2013.01); A61K 39/0008 (2013.01); A61K 39/001 (2013.01); A61K 39/4611 (2023.05); A61K 39/4621 (2023.05); A61K 39/46433 (2023.05); C12N 5/0636 (2013.01); C12N 5/0637 (2013.01); C12N 5/0667 (2013.01); A61K 2035/122 (2013.01); A61K 2035/124 (2013.01); C12N 2501/24 (2013.01);
Abstract

The present invention provides a population of connective tissue derived cells that respond to interferon-gamma (IFN-γ) by expressing indolamine-2,3-dioxygenase (IDO) for use in preventing, treating or ameliorating one or more symptoms associated with disorders in which modulation of a subject's immune system is beneficial, including, but not limited to, autoimmune diseases, inflammatory disorders, and immunologically mediated diseases including rejection of transplanted organs and tissues.


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