The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2025

Filed:

Sep. 06, 2022
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Nicole F. Steinmetz, San Diego, CA (US);

Frank Alexander Veliz, Cleveland, OH (US);

Brylee David B. Tiu, Cleveland, OH (US);

Assignee:

CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 39/00 (2006.01); A61K 39/385 (2006.01); A61K 39/39 (2006.01); A61P 35/00 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/6901 (2017.08); A61K 39/0011 (2013.01); A61K 39/385 (2013.01); A61K 39/39 (2013.01); A61P 35/00 (2018.01); A61K 2039/5258 (2013.01); A61K 2039/585 (2013.01); A61K 2039/622 (2013.01); A61K 2039/645 (2013.01); B82Y 5/00 (2013.01);
Abstract

A nanoparticle construct includes a plurality of plant virus or virus-like particles electrostatically coupled to a plurality of nanoparticles having a different surface charge than the plant virus or virus-like particles. The nanoparticle construct upon delivery to a subject can provide a sustained release of the plant virus or virus-like particles and/or nanoparticles to a cell or tissue of the subject.


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