The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2024
Filed:
Oct. 14, 2022
Applicant:
Myriad Genetics, Inc., Salt Lake City, UT (US);
Inventors:
Alexander Gutin, Salt Lake City, UT (US);
Julia Reid, Salt Lake City, UT (US);
Ralf Kronenwett, Salt Lake City, UT (US);
Marsel Scheer, Salt Lake City, UT (US);
Assignee:
MYRIAD INTERNATIONAL GMBH, Cologne, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G16B 20/00 (2019.01); G16B 25/10 (2019.01); G16H 20/10 (2018.01); G16H 50/20 (2018.01); G16H 70/60 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G16B 20/00 (2019.02); G16B 25/10 (2019.02); G16H 20/10 (2018.01); G16H 50/20 (2018.01); G16H 70/60 (2018.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01);
Abstract
Provided herein are methods for predicting chemotherapy benefit. The invention predicts chemotherapy benefit based on the expression analysis of biomarkers, e.g., RNA biomarker transcription analysis, taken from a tumor sample. The biomarker expression data can be combined with clinical variables, e.g., tumor size and nodal status, to generate a profile that predicts the benefit of including chemotherapy as a treatment decision.