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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12180525 B1

PDFFull Text
Date of Patent:
Dec. 31, 2024

Filed:

Jun. 22, 2022

Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids

Applicant:

Antheia Inc., Menlo Park, CA (US);

Inventors:

Christina D. Smolke, Menlo Park, CA (US);

Catherine Thodey, Mountain View, CA (US);

Isis Trenchard, Redwood City, CA (US);

Assignee:

Antheia, Inc., Menlo Park, CA (US);

Attorney:

Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.

Primary Examiner:

Ganapathirama Raghu

Int. Cl.
CPC ...
C12P 17/18 (2006.01); C12N 9/02 (2006.01); C12N 9/04 (2006.01); C12N 9/06 (2006.01); C12N 9/14 (2006.01); C12N 9/90 (2006.01); C12N 15/85 (2006.01); C12P 17/12 (2006.01);
U.S. Cl.
CPC ...
C12P 17/182 (2013.01); C12N 9/0006 (2013.01); C12N 9/0028 (2013.01); C12N 9/0071 (2013.01); C12N 9/14 (2013.01); C12N 9/90 (2013.01); C12N 15/85 (2013.01); C12P 17/12 (2013.01); C12P 17/18 (2013.01); C12Y 105/01027 (2013.01); C12Y 114/16002 (2013.01); C12Y 114/21004 (2013.01); C12N 2015/8518 (2013.01); C12Y 305/04016 (2013.01);
Abstract

A method of demethylizing an opioid to a nor-opioid is provided. The method comprises contacting an opioid with at least one enzyme. Contacting the opioid with the at least one enzyme converts the opioid to a nor-opioid. A method of converting a nor-opioid to a nal-opioid is provided. The method comprises contacting a nor-opioid with at least one enzyme. Contacting the nor-opioid with the at least one enzyme converts the nor-opioid to a nal-opioid.

Find Patent Forward Citations

Smolke, Christina. (2024). Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids (U.S. Patent No. 12180525). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12180525

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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