The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2024

Filed:

Jan. 16, 2021
Applicant:

Hamilton Bonaduz Ag, Bonaduz, CH;

Inventors:

Dirk Schoenfuss, Tamins, CH;

Frederic Juillerat, Paspels, CH;

Assignee:

Hamilton Bonaduz AG, Bonaduz, CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
C12M 23/14 (2013.01); C12M 23/20 (2013.01); C12M 23/26 (2013.01); C12M 23/28 (2013.01); C12M 29/18 (2013.01);
Abstract

A device for monitoring a biological process in a liquid medium includes a wall portion, a silanization layer and a sensor arrangement. The device attaches to a container of a bioreactor and can be used with disposable bioreactors. The wall portion is adapted to retain the liquid medium during operation of the bioreactor. A through-hole is disposed in the wall portion. A silanization layer covers the surface encircling the through-hole and the wall portion between the liquid medium and the wall portion. The sensor arrangement includes a glass layer, a substrate and an electrode. The glass layer is bonded by an adhesive to the silanization layer so as to cover the through-hole. The electrode is mounted on the substrate and measures electrical conductivity through the liquid medium. The sensor arrangement also includes an optical sensor that detects electromagnetic radiation that passes from the liquid medium through the glass layer.


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