The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2024
Filed:
Mar. 12, 2021
Applicants:
Wuxi Biologics (Shanghai) Co. Ltd., Shanghai, CN;
Wuxi Biologics Ireland Limited, Dublin, IE;
Inventors:
Assignees:
WUXI BIOLOGICS (SHANGHAI) CO. LTD., Shanghai, CN;
WUXI BIOLOGICS IRELAND LIMITED, Dublin, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61P 35/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); A61P 35/00 (2018.01); C07K 2317/21 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); G01N 2800/52 (2013.01);
Abstract
The present disclosure provides monoclonal antibodies against protein programmed cell death 1 ligand (PD-L1), which can block the binding of PD-L1 to PD-1, and therefore block the inhibitory function of PD-L1 on PD-1 expressing T cells. The antibodies of disclosure provide very potent agents for the treatment of multiple cancers via modulating human immune function.