The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2024
Filed:
Feb. 16, 2023
Applicant:
Sage Therapeutics, Inc., Cambridge, MA (US);
Inventors:
Gabriel Martinez Botella, Wayland, MA (US);
Francesco G. Salituro, Marlborough, MA (US);
Albert Jean Robichaud, Boston, MA (US);
Boyd L. Harrison, Princeton Junction, NJ (US);
Assignee:
Sage Therapeutics, Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07J 75/00 (2006.01); A61K 9/00 (2006.01); A61K 31/58 (2006.01); A61P 25/00 (2006.01); C07D 231/14 (2006.01); C07D 249/04 (2006.01); C07D 249/18 (2006.01); C07D 295/033 (2006.01); C07J 9/00 (2006.01); C07J 13/00 (2006.01); C07J 43/00 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 31/58 (2013.01); A61P 25/00 (2018.01); C07D 231/14 (2013.01); C07D 249/04 (2013.01); C07D 249/18 (2013.01); C07D 295/033 (2013.01); C07J 9/00 (2013.01); C07J 13/007 (2013.01); C07J 75/00 (2013.01);
Abstract
Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein, R, R, R, Rand A are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.