The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2024
Filed:
Apr. 29, 2024
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Feng Xu, Staten Island, NY (US);
Zhuqing Liu, Edison, NJ (US);
Richard Desmond, Readington, NJ (US);
Jeonghan Park, Whippany, NJ (US);
Alexei Kalinin, Morganville, NJ (US);
Birgit Kosjek, Westfield, NJ (US);
Hallena Strotman, Somerset, NJ (US);
Hongmei Li, Westfield, NJ (US);
Johannah Moncecchi, Waltham, MA (US);
MERCK SHARP & DOHME LLC, Rahway, NJ (US);
Abstract
The application is directed to efficient and economical processes as described in more detail below for the preparation of the beta 3 agonists of the formula of I-7 and intermediate compounds that can be used for making these agonists. The present disclosure relates to a process for making beta-3 agonists and intermediates using ketoreductase (KRED) biocatalyst enzymes and methods of using the biocatalysts.