The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2024

Filed:

Sep. 29, 2021
Applicants:

Endocyte, Inc., West Lafayette, IN (US);

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

Iontcho R Vlahov, West Lafayette, IN (US);

Christopher P Leamon, West Lafayette, IN (US);

Philip S. Low, West Lafayette, IN (US);

Garth L Parham, Largo, FL (US);

Qingshou Chen, West Lafayette, IN (US);

Assignees:

Purdue Research Foundation, West Lafayette, IN (US);

Endocyte, Inc., West Lafayette, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0497 (2013.01); A61K 51/04 (2013.01); A61K 51/0459 (2013.01); A61K 51/0482 (2013.01);
Abstract

Described herein are compounds, compositions, and methods for diagnosing and/or monitoring pathogenic disease using positron emission tomography. Also described are conjugates of the formula B-L-P, wherein B is a radical of a targeting agent selected from vitamin receptor binding ligands (such as folate), PSMA binding ligands, or PSMA inhibitors; L is a divalent linker comprising aspartic acid, lysine, or arginine, and P is a radical of an imaging agent or radiotherapy agent, such as a radionuclide or radionuclide containing group, or a radical of a compound capable of binding a radionuclide, such as a metal chelating group.


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