The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2024
Filed:
Mar. 08, 2019
Am-pharma B.v., Utrecht, NL;
Roelof Peter Pickkers, Utrecht, NL;
Ravindra Lall Mehta, Utrecht, NL;
Patrick Thomas Murray, Utrecht, NL;
Michael Joannidis, Utrecht, NL;
Erik Jan Van Den Berg, Utrecht, NL;
Jacques Salomon Robert Arend, Utrecht, NL;
AM-Pharma B.V., Utrecht, NL;
Abstract
The present disclosure relates to the use of alkaline phosphatases, and in particular improved alkaline phosphatases such as RecAP, for the prevention, treatment, cure, or amelioration of the symptoms of acute kidney injury caused, e.g., by sepsis. The application relates to methods of preserving renal function renal function, shortening the duration of renal replacement therapy, increasing the creatinine clearance, decreasing the risk of death in subjects with sepsis-associate acute kidney injury (SA-AKI) or at risk of SA-AKI.