The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2024

Filed:

Sep. 25, 2019
Applicant:

Emo Biomedicine Corp., New Taipei, TW;

Inventors:

Shing-Mou Lee, New Taipei, TW;

Hung-Hsuan Chen, New Taipei, TW;

Wan-Ling Lai, New Taipei, TW;

San-Ni Yu, New Taipei, TW;

Assignee:

EMO BIOMEDICINE CORP., New Taipei, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/12 (2015.01); A61K 35/28 (2015.01); A61P 19/02 (2006.01); A61P 37/06 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61P 19/02 (2018.01); A61P 37/06 (2018.01); G01N 33/5073 (2013.01);
Abstract

Disclosed herein is a method of identifying a plurality of mesenchymal stem cells (MSCs) that are therapeutic to a subject having an immune-related disease, for example, arthritis. According to embodiments of the present disclosure, the MSCs exhibiting to the immune-related disease are characterized in having an immunosuppressive protein binding value (IPBv) greater than 170 toward indoleamine 2,3-dioxygenase (IDO) after being exposed to 50-800 U/ml of IFN-γ. Also disclosed herein are uses of the identified MSCs for the manufacture of a medicament, and methods of treating an immune-related disease by use of the identified MSCs or medicament.


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