The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 31, 2024
Filed:
Jan. 27, 2016
Realinn Life Science Limited, Taoyuan, TW;
Jen Cheng Lin, Keelung, TW;
Chun-Chieh Lin, Taipei, TW;
Hsu-Tung Lee, Taichuang, TW;
Yu-Ming Fan, Taipei, TW;
Jui-Chi Tsai, Taipei, TW;
Ying-Chi Du, Chiayi, TW;
REALINN LIFE SCIENCE LIMITED, Taoyuan, TW;
Abstract
The present invention relates to a novel type of PPARγ modulator having a pyrimido[5,4-d]pyrimidine main structure. The PPARγ modulator can enhance the expression and nuclear translocation of PPARγ in cells. The present invention also relates to a pharmaceutical composition comprising the PPARγ modulator of the invention encapsulated in a pharmaceutically acceptable cell-penetrating drug delivery system so that it can be directly delivered into cells. The present invention thus provides a method of preventing or treating PPARγ-related disorders or conditions comprising administering to a subject in need thereof a therapeutically effective amount of the PPARγ modulator of the invention or the pharmaceutical composition of the invention.