The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 31, 2024

Filed:

Aug. 27, 2021
Applicants:

The Regents of the University of California, Oakland, CA (US);

The Brigham and Women's Hospital, Boston, MA (US);

Inventors:

Seung-Schik Yoo, Wellesley, MA (US);

Alexander Bystritsky, Sherman Oaks, CA (US);

Nathan McDannold, Jamaica Plain, MA (US);

Ferenc A. Jolesz, Brookline, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/055 (2006.01); A61B 6/03 (2006.01); A61N 7/00 (2006.01); A61N 7/02 (2006.01); A61B 90/00 (2016.01);
U.S. Cl.
CPC ...
A61B 5/0036 (2018.08); A61B 5/0042 (2013.01); A61B 5/055 (2013.01); A61B 6/037 (2013.01); A61N 7/00 (2013.01); A61N 7/02 (2013.01); A61B 2090/374 (2016.02); A61N 2007/0021 (2013.01); A61N 2007/0026 (2013.01); A61N 2007/0078 (2013.01);
Abstract

A system comprises an ultrasound subsystem and a magnetic resonance imaging (MRI) subsystem. The ultrasound subsystem applies pulses of focused ultrasound having one or more parameters to an identified location in a subject that is to receive treatment. The parameters are determined in accordance with a magnetic resonance guided focused ultrasound (MRgFUS) treatment plan. The MRI subsystem acquires functional image data corresponding to the identified location concurrently with the applied pulses of focused ultrasound. The MRI subsystem obtains a reconstructed series of functional images of the subject using the functional image data. The functional images are indicative of a first region within the identified location in which neuronal activity has been modified by the applied pulses. The system is configured to adjust one or more parameters of the MRgFUS treatment plan using the reconstructed series of functional images.


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