The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Apr. 25, 2021
Beijing Gigaceuticals Tech. Co. Ltd, Beijing, CN;
Peking University, Beijing, CN;
Zhengwei Xie, Beijing, CN;
Jie Zhu, Beijing, CN;
Jingxiang Wang, Beijing, CN;
Mingjing Gao, Beijing, CN;
Zhurui Liu, Beijing, CN;
BEIJING GIGACEUTICALS TECH. CO. LTD, Beijing, CN;
PEKING UNIVERSITY, Beijing, CN;
Abstract
The present disclosure provides a compound function prediction method based on a neural network and a connectivity map (CMAP) algorithm. The compound function prediction method is used to predict an efficacy of a compound, and the compound function prediction method includes the following steps: constructing a compound molecule-encoding vector neural network; constructing and training an encoding vector-marker gene expression variation deep neural network; constructing and training a marker gene expression level or gene expression variation-whole genome gene expression level or gene expression variation neural network; constructing upregulated and downregulated gene sets of a disease or a phenotype; and evaluating a correlation between the compound and the disease or the phenotype.