The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Mar. 26, 2019
Applicants:

The Trustees of Princeton University, Princeton, NJ (US);

The Simons Foundation, Inc., New York, NY (US);

Inventors:

Jian Zhou, Dallas, TX (US);

Chandra Theesfeld, Princeton, NJ (US);

Olga G. Troyanskaya, Princeton, NJ (US);

Assignees:

The Trustees of Princeton University, Princeton, NJ (US);

The Simons Foundation, Inc., New York, NY (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16B 20/20 (2019.01); G16B 20/50 (2019.01); G16B 25/10 (2019.01);
U.S. Cl.
CPC ...
G16B 20/20 (2019.02); G16B 20/50 (2019.02); G16B 25/10 (2019.02);
Abstract

Processes to determine the effect of genetic sequence on gene expression levels are described. Generally, models are used to determine spatial chromatin profile from genetic sequence, which can be used in several downstream applications. The effect of the spatial chromatin profile on gene expression is also determined in some instances. Various methods further develop research tools, perform diagnostics, and treat individuals based on sequence effects on gene expression levels.


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