The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 24, 2024
Filed:
Jan. 15, 2019
Applicant:
Epiaxis Therapeutics Pty Ltd, Herston, AU;
Inventor:
Sudha Rao, Red Hill, AU;
Assignee:
EPIAXIS THERAPEUTICS PTY LTD, Herston, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57492 (2013.01); C07K 16/2827 (2013.01); G01N 2333/70532 (2013.01); G01N 2440/10 (2013.01); G01N 2440/12 (2013.01);
Abstract
Disclosed are methods and agents for predicting responses to therapy. More particularly, the present disclosure relates to methods and agents for detecting different forms of Programmed Death Ligand-1 (PD-L1) in cancer cells, which are useful for detecting location of PD-L1 in a cellular compartment (e.g., nucleus, cytoplasm, cell membrane) of a cancer cell, for predicting the likelihood of response of a cancer cell to therapy including immunotherapy, for stratifying a cancer patient as a likely responder or non-responder to a therapy, for managing treatment of a cancer patient, and for predicting clinical outcomes.