The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 24, 2024

Filed:

Mar. 12, 2024
Applicant:

Velanidi Technologies Llc, Portland, OR (US);

Inventors:

Jane Ni, Portland, OR (US);

David Shykind, Buxton, OR (US);

Devin Wiley, Hillsboro, OR (US);

Assignee:

VELANIDI TECHNOLOGIES LLC, Portland, OR (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); C12Q 1/6804 (2018.01);
U.S. Cl.
CPC ...
G01N 33/54373 (2013.01); C12Q 1/6804 (2013.01);
Abstract

A method of using a device to detect a target entity in an environment includes introducing the device into the environment. The device includes first and second conductive surfaces, with a first molecular wire electrically coupling the first conductive surface to a capture agent that can interact with the target entity, and a second molecular wire electrically coupling the second conductive surface to a reference compound. The first and the second molecular wires comprise oligonucleotide multiplexes having identical nucleobase sequences and opposite absolute configuration. The method also includes detecting, by the device, an interaction between the capture agent and the target entity, at least in part by amplifying a differential voltage between the first and second conductive surfaces and detecting the interaction based on the differential voltage.


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